The 6 Best Supplements for Depression

Depression affects millions of adults in the United States, and the COVID-19 pandemic has contributed to its increasing prevalence. While there are various effective treatments for depression, including therapy and medication, some individuals may also consider using dietary supplements as adjunctive treatments. It’s important to note that supplements should not be used as standalone treatments and must be approached with caution.  We will explore the 6 best supplements for depression, as recommended by a dietitian, and provide an explanation of their products and benefits.

Best Omega-3: Carlson Elite EPA Gems Omega-3 fatty acids, specifically eicosapentaenoic acid (EPA), have shown promise in treating depression. Carlson Elite EPA Gems provide the recommended dose of 1,000 mg of EPA, supported by research. While not effective on its own, it can be beneficial when taken alongside antidepressant medications. The supplement is approved by and holds certifications for quality and purity. It is important to note that Carlson Elite EPA Gems are not suitable for individuals with fish allergies and are not suitable for vegetarians or vegans.

Best Vitamin D: Nature Made Vitamin D3 2000 IU, Low vitamin D levels have been linked to depression. Nature Made Vitamin D3 offers a range of doses, allowing users to find the most effective dose for their needs. It is essential to have your vitamin D levels checked before considering supplementation. While it may offer mild mood benefits, it is important to remember that vitamin D supplements may not provide significant relief for everyone.

Best St. John’s Wort: Nature’s Way Perika St. John’s Wort St. has shown efficacy in treating mild to moderate depression. Nature’s Way Perika St. John’s Wort provides a research-backed dose of 3% hyperforin, a key compound in the herb. When choosing a St. John’s Wort supplement, it is important to consider the proper dose and the inclusion of all parts of the plant. Nature’s Way Perika St. John’s Wort has undergone third-party testing and is free from major allergens. However, caution is advised as St. John’s Wort interacts with various medications and may worsen symptoms in some individuals.

Best B-Vitamin: Thorne Research B-Complex #6 Vitamin B deficiencies have been linked to depressive symptoms, making B-complex supplements a potential option. Thorne Research B-Complex #6 is known for its quality and is NSF Certified for Sport. It contains active forms of B vitamins, allowing for better absorption. However, it is important to note that B-vitamin supplementation alone may not effectively treat depression, especially for non-deficient individuals. Consulting with a healthcare provider is recommended.

Best Folate: Thorne Research 5-MTHF 15 Mg, has shown potential benefits in reducing depressive symptoms, particularly when used alongside antidepressants. Thorne Research 5-MTHF 15 Mg provides the active form of folate in a research-supported dose. It is crucial to consult with a healthcare provider before starting folate supplementation, as it may not be suitable as a standalone treatment.

Best S-adenosyl methionine (SAMe): Nature’s Trove SAM-e SAMe is a compound involved in the regulation of hormones and neurotransmitter production.  It have some benefits for mild to moderate depression. Nature’s Trove SAM-e is a reliable supplement containing 400 mg per serving. It is allergen-free, undergoes third-party testing, and is free from artificial additives. However, SAMe may have side effects and should be used under the guidance of a healthcare provider, particularly if you have pre-existing health conditions or are taking other medications.